Cargando…

Identification of the Xenopus DNA2 protein as a major nuclease for the 5′→3′ strand-specific processing of DNA ends

The first step of homology-dependent DNA double-strand break (DSB) repair is the 5′ strand-specific processing of DNA ends to generate 3′ single-strand tails. Despite extensive effort, the nuclease(s) that is directly responsible for the resection of 5′ strands in eukaryotic cells remains elusive. U...

Descripción completa

Detalles Bibliográficos
Autores principales: Liao, Shuren, Toczylowski, Thomas, Yan, Hong
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577336/
https://www.ncbi.nlm.nih.gov/pubmed/18820296
http://dx.doi.org/10.1093/nar/gkn616