Hairpin structures formed by alpha satellite DNA of human centromeres are cleaved by human topoisomerase IIα

Although centromere function has been conserved through evolution, apparently no interspecies consensus DNA sequence exists. Instead, centromere DNA may be interconnected through the formation of certain DNA structures creating topological binding sites for centromeric proteins. DNA topoisomerase II...

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Detalles Bibliográficos
Autores principales: Jonstrup, Anette Thyssen, Thomsen, Tina, Wang, Yong, Knudsen, Birgitta R., Koch, Jørn, Andersen, Anni H.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577340/
https://www.ncbi.nlm.nih.gov/pubmed/18824478
http://dx.doi.org/10.1093/nar/gkn640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577340/
https://www.ncbi.nlm.nih.gov/pubmed/18824478
http://dx.doi.org/10.1093/nar/gkn640

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