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Hairpin structures formed by alpha satellite DNA of human centromeres are cleaved by human topoisomerase IIα
Although centromere function has been conserved through evolution, apparently no interspecies consensus DNA sequence exists. Instead, centromere DNA may be interconnected through the formation of certain DNA structures creating topological binding sites for centromeric proteins. DNA topoisomerase II...
Autores principales: | Jonstrup, Anette Thyssen, Thomsen, Tina, Wang, Yong, Knudsen, Birgitta R., Koch, Jørn, Andersen, Anni H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577340/ https://www.ncbi.nlm.nih.gov/pubmed/18824478 http://dx.doi.org/10.1093/nar/gkn640 |
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