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Rapid regulation of telomere length is mediated by poly(ADP-ribose) polymerase-1

Shelterin/telosome is a multi-protein complex at mammalian telomeres, anchored to the double-stranded region by the telomeric-repeat binding factors-1 and -2. In vitro modification of these proteins by poly(ADP-ribosyl)ation through poly(ADP-ribose) polymerases-5 (tankyrases) and -1/-2, respectively...

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Detalles Bibliográficos
Autores principales: Beneke, Sascha, Cohausz, Odile, Malanga, Maria, Boukamp, Petra, Althaus, Felix, Bürkle, Alexander
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577345/
https://www.ncbi.nlm.nih.gov/pubmed/18835851
http://dx.doi.org/10.1093/nar/gkn615