Use of high throughput qPCR screening to rapidly clone low frequency tumour specific T-cells from peripheral blood for adoptive immunotherapy

BACKGROUND: The adoptive transfer of autologous tumor reactive lymphocytes can mediate significant tumor regression in some patients with refractory metastatic cancer. However, a significant obstacle for this promising therapy has been the availability of highly efficient methods to rapidly isolate...

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Detalles Bibliográficos
Autores principales: Kammula, Udai S, Serrano, Oscar K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577625/
https://www.ncbi.nlm.nih.gov/pubmed/18937837
http://dx.doi.org/10.1186/1479-5876-6-60

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577625/
https://www.ncbi.nlm.nih.gov/pubmed/18937837
http://dx.doi.org/10.1186/1479-5876-6-60

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