Development of automated brightfield double In Situ hybridization (BDISH) application for HER2 gene and chromosome 17 centromere (CEN 17) for breast carcinomas and an assay performance comparison to manual dual color HER2 fluorescence In Situ hybridization (FISH)

BACKGROUND: Human epidermal growth factor receptor 2 (HER2) fluorescence in situ hybridization (FISH) is a quantitative assay for selecting breast cancer patients for trastuzumab therapy. However, current HER2 FISH procedures are labor intensive, manual methods that require skilled technologists and...

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Detalles Bibliográficos
Autores principales: Nitta, Hiroaki, Hauss-Wegrzyniak, Beatrice, Lehrkamp, Megan, Murillo, Adrian E, Gaire, Fabien, Farrell, Michael, Walk, Eric, Penault-Llorca, Frederique, Kurosumi, Masafumi, Dietel, Manfred, Wang, Lin, Loftus, Margaret, Pettay, James, Tubbs, Raymond R, Grogan, Thomas M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577627/
https://www.ncbi.nlm.nih.gov/pubmed/18945356
http://dx.doi.org/10.1186/1746-1596-3-41

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577627/
https://www.ncbi.nlm.nih.gov/pubmed/18945356
http://dx.doi.org/10.1186/1746-1596-3-41

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