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Evolution Acts on Enhancer Organization to Fine-Tune Gradient Threshold Readouts

The elucidation of principles governing evolution of gene regulatory sequence is critical to the study of metazoan diversification. We are therefore exploring the structure and organizational constraints of regulatory sequences by studying functionally equivalent cis-regulatory modules (CRMs) that h...

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Detalles Bibliográficos
Autores principales: Crocker, Justin, Tamori, Yoichiro, Erives, Albert
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577699/
https://www.ncbi.nlm.nih.gov/pubmed/18986212
http://dx.doi.org/10.1371/journal.pbio.0060263