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Evolution Acts on Enhancer Organization to Fine-Tune Gradient Threshold Readouts
The elucidation of principles governing evolution of gene regulatory sequence is critical to the study of metazoan diversification. We are therefore exploring the structure and organizational constraints of regulatory sequences by studying functionally equivalent cis-regulatory modules (CRMs) that h...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577699/ https://www.ncbi.nlm.nih.gov/pubmed/18986212 http://dx.doi.org/10.1371/journal.pbio.0060263 |