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A defect of sphingolipid metabolism modifies the properties of normal appearing white matter in multiple sclerosis
Maintaining the appropriate complement and content of lipids in cellular membranes is critical for normal neural function. Accumulating evidence suggests that even subtle perturbations in the lipid content of neurons and myelin can disrupt their function and may contribute to myelin and axonal degra...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577809/ https://www.ncbi.nlm.nih.gov/pubmed/18772223 http://dx.doi.org/10.1093/brain/awn190 |