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Structural and Thermodynamic Approach to Peptide Immunogenicity

In the conventional paradigm of humoral immunity, B cells recognize their cognate antigen target in its native form. However, it is well known that relatively unstable peptides bearing only partial structural resemblance to the native protein can trigger antibodies recognizing higher-order structure...

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Detalles Bibliográficos
Autores principales: Camacho, Carlos J., Katsumata, Yasuhiro, Ascherman, Dana P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577884/
https://www.ncbi.nlm.nih.gov/pubmed/19023401
http://dx.doi.org/10.1371/journal.pcbi.1000231