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Structural and Thermodynamic Approach to Peptide Immunogenicity
In the conventional paradigm of humoral immunity, B cells recognize their cognate antigen target in its native form. However, it is well known that relatively unstable peptides bearing only partial structural resemblance to the native protein can trigger antibodies recognizing higher-order structure...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577884/ https://www.ncbi.nlm.nih.gov/pubmed/19023401 http://dx.doi.org/10.1371/journal.pcbi.1000231 |