Hypermutability of Damaged Single-Strand DNA Formed at Double-Strand Breaks and Uncapped Telomeres in Yeast Saccharomyces cerevisiae

The major DNA repair pathways operate on damage in double-strand DNA because they use the intact strand as a template after damage removal. Therefore, lesions in transient single-strand stretches of chromosomal DNA are expected to be especially threatening to genome stability. To test this hypothesi...

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Detalles Bibliográficos
Autores principales: Yang, Yong, Sterling, Joan, Storici, Francesca, Resnick, Michael A., Gordenin, Dmitry A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577886/
https://www.ncbi.nlm.nih.gov/pubmed/19023402
http://dx.doi.org/10.1371/journal.pgen.1000264

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577886/
https://www.ncbi.nlm.nih.gov/pubmed/19023402
http://dx.doi.org/10.1371/journal.pgen.1000264

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