Cargando…

Hypermutability of Damaged Single-Strand DNA Formed at Double-Strand Breaks and Uncapped Telomeres in Yeast Saccharomyces cerevisiae

The major DNA repair pathways operate on damage in double-strand DNA because they use the intact strand as a template after damage removal. Therefore, lesions in transient single-strand stretches of chromosomal DNA are expected to be especially threatening to genome stability. To test this hypothesi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Yong, Sterling, Joan, Storici, Francesca, Resnick, Michael A., Gordenin, Dmitry A.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577886/ https://www.ncbi.nlm.nih.gov/pubmed/19023402 http://dx.doi.org/10.1371/journal.pgen.1000264

Ejemplares similares

Hypermutation in single-stranded DNA
por: Saini, Natalie, et al.
Publicado: (2020)

Base Damage within Single-Strand DNA Underlies In Vivo Hypermutability Induced by a Ubiquitous Environmental Agent
por: Chan, Kin, et al.
Publicado: (2012)

Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation
por: Sakofsky, Cynthia J., et al.
Publicado: (2019)

Correction: Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation
por: Sakofsky, Cynthia J., et al.
Publicado: (2020)

The DNA-damage signature in Saccharomyces cerevisiae is associated with single-strand breaks in DNA
por: Fry, Rebecca C, et al.
Publicado: (2006)

DNA Double-Strand Breaks: Prior to but not Sufficient in Targeting Hypermutation
por: Bross, Linda, et al.
Publicado: (2002)

Characteristics of replication-independent endogenous double-strand breaks in Saccharomyces cerevisiae
por: Pongpanich, Monnat, et al.
Publicado: (2014)

Alkylation Base Damage Is Converted into Repairable Double-Strand Breaks and Complex Intermediates in G2 Cells Lacking AP Endonuclease
por: Ma, Wenjian, et al.
Publicado: (2011)

The prevalence of killer yeasts and double-stranded RNAs in the budding yeast Saccharomyces cerevisiae
por: Crabtree, Angela M, et al.
Publicado: (2023)

DNA strand-exchange patterns associated with double-strand break-induced and spontaneous mitotic crossovers in Saccharomyces cerevisiae
por: Hum, Yee Fang, et al.
Publicado: (2018)

Replication-Independent Endogenous DNA Double-Strand Breaks in Saccharomyces cerevisiae Model
por: Thongsroy, Jirapan, et al.
Publicado: (2013)

Evidence for double-strand break mediated mitochondrial DNA replication in Saccharomyces cerevisiae
por: Prasai, Kanchanjunga, et al.
Publicado: (2017)

Histone methyltransferase Dot1 and Rad9 inhibit single-stranded DNA accumulation at DSBs and uncapped telomeres
por: Lazzaro, Federico, et al.
Publicado: (2008)

Mapping Meiotic Single-Strand DNA Reveals a New Landscape of DNA Double-Strand Breaks in Saccharomyces cerevisiae
por: Buhler, Cyril, et al.
Publicado: (2007)

Uncapping and Deregulation of Telomeres Lead to Detrimental Cellular Consequences in Yeast
por: Smith, Christopher D., et al.
Publicado: (1999)

Resection is responsible for loss of transcription around a double-strand break in Saccharomyces cerevisiae
por: Manfrini, Nicola, et al.
Publicado: (2015)

Role of Double-Strand Break End-Tethering during Gene Conversion in Saccharomyces cerevisiae
por: Jain, Suvi, et al.
Publicado: (2016)

Endogenous single-strand DNA breaks at RNA polymerase II promoters in Saccharomyces cerevisiae
por: Hegedüs, Éva, et al.
Publicado: (2018)

DNA Double Strand Breaks Occur Independent of AID in Hypermutating Ig Genes
por: Bross, Linda, et al.
Publicado: (2003)

Correction: Mapping Meiotic Single-Strand DNA Reveals a New Landscape of DNA Double-Strand Breaks in Saccharomyces cerevisiae
por: Buhler, Cyril, et al.
Publicado: (2008)

A multistep genomic screen identifies new genes required for repair of DNA double-strand breaks in Saccharomyces cerevisiae
por: McKinney, Jennifer Summers, et al.
Publicado: (2013)

To Nick or Not to Nick: Comparison of I-SceI Single- and Double-Strand Break-Induced Recombination in Yeast and Human Cells
por: Katz, Samantha S., et al.
Publicado: (2014)

Oxidative stress-induced mutagenesis in single-strand DNA occurs primarily at cytosines and is DNA polymerase zeta-dependent only for adenines and guanines
por: Degtyareva, Natalya P., et al.
Publicado: (2013)

Apparent Epigenetic Meiotic Double-Strand-Break Disparity in Saccharomyces cerevisiae: A Meta-Analysis
por: Stahl, Franklin W., et al.
Publicado: (2016)

When the Ends Justify the Means: Regulation of Telomere Addition at Double-Strand Breaks in Yeast
por: Hoerr, Remington E., et al.
Publicado: (2021)

TERRA and Telomere Maintenance in the Yeast Saccharomyces cerevisiae
por: Zeinoun, Bechara, et al.
Publicado: (2023)

Suppression of Allelic Recombination and Aneuploidy by Cohesin Is Independent of Chk1 in Saccharomyces cerevisiae
por: Covo, Shay, et al.
Publicado: (2014)

Signaling of double strand breaks and deprotected telomeres in Arabidopsis
por: Amiard, Simon, et al.
Publicado: (2013)

Live cell monitoring of double strand breaks in S. cerevisiae
por: Waterman, David P., et al.
Publicado: (2019)

Efficient DNA double-strand break formation at single or multiple defined sites in the Saccharomyces cerevisiae genome
por: Gnügge, Robert, et al.
Publicado: (2020)

Mutational signatures of redox stress in yeast single-strand DNA and of aging in human mitochondrial DNA share a common feature
por: Degtyareva, Natalya P., et al.
Publicado: (2019)

DNA Replication Through Strand Displacement During Lagging Strand DNA Synthesis in Saccharomyces cerevisiae
por: Giannattasio, Michele, et al.
Publicado: (2019)

Role of Saccharomyces Single-Stranded DNA-Binding Protein RPA in the Strand Invasion Step of Double-Strand Break Repair
por: Wang, Xuan, et al.
Publicado: (2004)

Multiple roles for Mre11 at uncapped telomeres
por: Deng, Yibin, et al.
Publicado: (2009)

AID Mediates Hypermutation by Deaminating Single Stranded DNA
por: Dickerson, Sarah K., et al.
Publicado: (2003)

Rad10 exhibits lesion-dependent genetic requirements for recruitment to DNA double-strand breaks in Saccharomyces cerevisiae
por: Moore, Destaye M., et al.
Publicado: (2009)

Mrc1 protects uncapped budding yeast telomeres from exonuclease EXO1
por: Tsolou, Avgi, et al.
Publicado: (2007)

The Mph1 Helicase Can Promote Telomere Uncapping and Premature Senescence in Budding Yeast
por: Luke-Glaser, Sarah, et al.
Publicado: (2012)

MRE11 Function in Response to Topoisomerase Poisons Is Independent of its Function in Double-Strand Break Repair in Saccharomyces cerevisiae
por: Hamilton, Nicolle K., et al.
Publicado: (2010)

Members of the RAD52 Epistasis Group Contribute to Mitochondrial Homologous Recombination and Double-Strand Break Repair in Saccharomyces cerevisiae
por: Stein, Alexis, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_tssoveh0g6j596ccjl8onp6g91