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Dissection of a QTL Hotspot on Mouse Distal Chromosome 1 that Modulates Neurobehavioral Phenotypes and Gene Expression

A remarkably diverse set of traits maps to a region on mouse distal chromosome 1 (Chr 1) that corresponds to human Chr 1q21–q23. This region is highly enriched in quantitative trait loci (QTLs) that control neural and behavioral phenotypes, including motor behavior, escape latency, emotionality, sei...

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Detalles Bibliográficos
Autores principales: Mozhui, Khyobeni, Ciobanu, Daniel C., Schikorski, Thomas, Wang, Xusheng, Lu, Lu, Williams, Robert W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577893/
https://www.ncbi.nlm.nih.gov/pubmed/19008955
http://dx.doi.org/10.1371/journal.pgen.1000260