Human Skin Culture as an Ex Vivo Model for Assessing the Fibrotic Effects of Insulin-Like Growth Factor Binding Proteins

Systemic sclerosis (SSc) is a connective tissue disease of unknown etiology. A hallmark of SSc is fibrosis of the skin and internal organs. We recently demonstrated increased expression of IGFBP-3 and IGFBP-5 in primary cultures of fibroblasts from the skin of patients with SSc. In vitro, IGFBP-3 an...

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Detalles Bibliográficos
Autores principales: Yasuoka, Hidekata, Larregina, Adriana T., Yamaguchi, Yukie, Feghali-Bostwick, Carol A.
Formato: Texto
Lenguaje:English
Publicado: Bentham Science Publishers Ltd. 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577950/
https://www.ncbi.nlm.nih.gov/pubmed/19088866
http://dx.doi.org/10.2174/1874312900802010017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577950/
https://www.ncbi.nlm.nih.gov/pubmed/19088866
http://dx.doi.org/10.2174/1874312900802010017

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