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The role of endogenous gastrin in the development of enterochromaffin-like cell carcinoid tumors in Mastomys natalensis: a study with the specific gastrin receptor antagonist AG-041R.

We examined the effects of a newly synthesized gastrin receptor antagonist, AG-041R, on the growth of enterochromaffin-like (ECL) carcinoid tumors in Mastomys natalensis both in vitro and in vivo. AG-041R was as potent as the well known gastrin antagonist L365,260 in inhibiting not only the gastrin-...

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Detalles Bibliográficos
Autores principales: Chiba, T., Kinoshita, Y., Sawada, M., Kishi, K., Baba, A., Hoshino, E.
Formato: Texto
Lenguaje:English
Publicado: Yale Journal of Biology and Medicine 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2578989/
https://www.ncbi.nlm.nih.gov/pubmed/10461356