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Lack of association of two common polymorphisms on 9p21 with risk of coronary heart disease and myocardial infarction; results from a prospective cohort study

BACKGROUND: Recent genome wide association (GWA) studies identified two Single Nucleotide Polymorphisms (SNP) (rs10757278 and rs10757274) in the region of the CDK2NA and CDK2NB genes to be consistently associated with the risks of coronary heart disease (CHD) and myocardial infarction (MI). We exami...

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Detalles Bibliográficos
Autores principales: Dehghan, Abbas, van Hoek, Mandy, Sijbrands, Eric JG, Oostra, Ben A, Hofman, Albert, van Duijn, Cornelia M, Witteman, Jacqueline CM
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579294/
https://www.ncbi.nlm.nih.gov/pubmed/18925945
http://dx.doi.org/10.1186/1741-7015-6-30