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Activation and detection of HTLV-I Tax-specific CTLs by Epitope expressing Single-Chain Trimers of MHC Class I in a rat model

BACKGROUND: Human T cell leukemia virus type I (HTLV-I) causes adult T-cell leukemia (ATL) in infected individuals after a long incubation period. Immunological studies have suggested that insufficient host T cell response to HTLV-I is a potential risk factor for ATL. To understand the relationship...

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Detalles Bibliográficos
Autores principales: Ohashi, Takashi, Nagai, Mika, Okada, Hiroyuki, Takayanagi, Ryo, Shida, Hisatoshi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579301/
https://www.ncbi.nlm.nih.gov/pubmed/18840303
http://dx.doi.org/10.1186/1742-4690-5-90