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Dysregulation of Mitochondrial Dynamics and the Muscle Transcriptome in ICU Patients Suffering from Sepsis Induced Multiple Organ Failure

BACKGROUND: Septic patients treated in the intensive care unit (ICU) often develop multiple organ failure including persistent skeletal muscle dysfunction which results in the patient's protracted recovery process. We have demonstrated that muscle mitochondrial enzyme activities are impaired in...

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Detalles Bibliográficos
Autores principales: Fredriksson, Katarina, Tjäder, Inga, Keller, Pernille, Petrovic, Natasa, Ahlman, Bo, Schéele, Camilla, Wernerman, Jan, Timmons, James A., Rooyackers, Olav
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579334/
https://www.ncbi.nlm.nih.gov/pubmed/18997871
http://dx.doi.org/10.1371/journal.pone.0003686