Treatment of Late Stage Disease in a Model of Arenaviral Hemorrhagic Fever: T-705 Efficacy and Reduced Toxicity Suggests an Alternative to Ribavirin

A growing number of arenaviruses are known to cause viral hemorrhagic fever (HF), a severe and life-threatening syndrome characterized by fever, malaise, and increased vascular permeability. Ribavirin, the only licensed antiviral indicated for the treatment of certain arenaviral HFs, has had mixed s...

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Detalles Bibliográficos
Autores principales: Gowen, Brian B., Smee, Donald F., Wong, Min-Hui, Hall, Jeffery O., Jung, Kie-Hoon, Bailey, Kevin W., Stevens, John R., Furuta, Yousuke, Morrey, John D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579488/
https://www.ncbi.nlm.nih.gov/pubmed/19008960
http://dx.doi.org/10.1371/journal.pone.0003725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579488/
https://www.ncbi.nlm.nih.gov/pubmed/19008960
http://dx.doi.org/10.1371/journal.pone.0003725

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