Clathrin and LRP-1-Independent Constitutive Endocytosis and Recycling of uPAR

BACKGROUND: The urokinase receptor (uPAR/CD87) is highly expressed in malignant tumours. uPAR, as a GPI anchored protein, is preferentially located at the cell surface, where it interacts with its ligands urokinase (uPA) and the extracellular matrix protein vitronectin, thus promoting plasmin genera...

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Detalles Bibliográficos
Autores principales: Cortese, Katia, Sahores, Macarena, Madsen, Chris D., Tacchetti, Carlo, Blasi, Francesco
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579578/
https://www.ncbi.nlm.nih.gov/pubmed/19008962
http://dx.doi.org/10.1371/journal.pone.0003730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579578/
https://www.ncbi.nlm.nih.gov/pubmed/19008962
http://dx.doi.org/10.1371/journal.pone.0003730

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