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Clathrin and LRP-1-Independent Constitutive Endocytosis and Recycling of uPAR
BACKGROUND: The urokinase receptor (uPAR/CD87) is highly expressed in malignant tumours. uPAR, as a GPI anchored protein, is preferentially located at the cell surface, where it interacts with its ligands urokinase (uPA) and the extracellular matrix protein vitronectin, thus promoting plasmin genera...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579578/ https://www.ncbi.nlm.nih.gov/pubmed/19008962 http://dx.doi.org/10.1371/journal.pone.0003730 |