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The in vivo properties of STX243: a potent angiogenesis inhibitor in breast cancer

The steroidal-based drug 2-ethyloestradiol-3,17-O,O-bis-sulphamate (STX243) has been developed as a potent antiangiogenic and antitumour compound. The objective of this study was to ascertain whether STX243 is more active in vivo than the clinically relevant drug 2-methoxyoestradiol (2-MeOE2) and th...

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Detalles Bibliográficos
Autores principales: Parsons, M F C, Foster, P A, Chander, S K, Jhalli, R, Newman, S P, Leese, M P, Potter, B V L, Purohit, A, Reed, M J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579677/
https://www.ncbi.nlm.nih.gov/pubmed/18841154
http://dx.doi.org/10.1038/sj.bjc.6604707