Activation of Slo1 BK channels by Mg(2+) coordinated between the voltage sensor and the RCK1 domains

The voltage sensor domain (VSD) and the ligand sensor (cytoplasmic domain) of BK channels synergistically control channel activities, thereby integrating electrical and chemical signals for cell function. Studies show that intracellular Mg(2+) mediates the interaction between these sensory domains t...

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Detalles Bibliográficos
Autores principales: Yang, Huanghe, Shi, Jingyi, Zhang, Guohui, Yang, Junqiu, Delaloye, Kelli, Cui, Jianmin
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579968/
https://www.ncbi.nlm.nih.gov/pubmed/18931675
http://dx.doi.org/10.1038/nsmb.1507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579968/
https://www.ncbi.nlm.nih.gov/pubmed/18931675
http://dx.doi.org/10.1038/nsmb.1507

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