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Low Frequency and Variability of FLT3 Mutations in Korean Patients with Acute Myeloid Leukemia

FLT3 mutations are common genetic changes, and are reported to have prognostic significance in acute myeloid leukemia (AML). The FLT3 internal tandem duplication (ITD) and the D835 activating mutation in the tyrosine kinase domain (TKD) were analyzed by polymerase chain reaction (PCR) in the genomic...

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Detalles Bibliográficos
Autores principales: Bang, Soo-Mee, Ahn, Jeong Yeal, Park, Jiyoon, Park, Se Hoon, Park, Jinny, Cho, Eun Kyung, Shin, Dong Bok, Lee, Jae Hoon, Yoo, Soo Jin, Jeon, In Sang, Kim, Yeo-Kyeoung, Kim, Hyeoung Joon, Kim, Hee-Nam, Lee, Il-Kwon, Kang, Hyoung Jin, Shin, Hee Young, Ahn, Hyo Seop
Formato: Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2580007/
https://www.ncbi.nlm.nih.gov/pubmed/18955790
http://dx.doi.org/10.3346/jkms.2008.23.5.833