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Potential Relevance of α(1)-Adrenergic Receptor Autoantibodies in Refractory Hypertension

BACKGROUND: Agonistic autoantibodies directed at the α(1)-adrenergic receptor (α(1)-AAB) have been described in patients with hypertension. We implied earlier that α(1)-AAB might have a mechanistic role and could represent a therapeutic target. METHODOLOGY/PRINCIPAL FINDINGS: To pursue the issue, we...

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Detalles Bibliográficos
Autores principales: Wenzel, Katrin, Haase, Hannelore, Wallukat, Gerd, Derer, Wolfgang, Bartel, Sabine, Homuth, Volker, Herse, Florian, Hubner, Norbert, Schulz, Herbert, Janczikowski, Marion, Lindschau, Carsten, Schroeder, Christoph, Verlohren, Stefan, Morano, Ingo, Muller, Dominik N., Luft, Friedrich C., Dietz, Rainer, Dechend, Ralf, Karczewski, Peter
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2580028/
https://www.ncbi.nlm.nih.gov/pubmed/19011682
http://dx.doi.org/10.1371/journal.pone.0003742