HLA-DM Mediates Epitope Selection by a “Compare-Exchange” Mechanism when a Potential Peptide Pool Is Available

BACKGROUND: HLA-DM (DM) mediates exchange of peptides bound to MHC class II (MHCII) during the epitope selection process. Although DM has been shown to have two activities, peptide release and MHC class II refolding, a clear characterization of the mechanism by which DM facilitates peptide exchange...

Descripción completa

Detalles Bibliográficos
Autores principales: Ferrante, Andrea, Anderson, Matthew W., Klug, Candice S., Gorski, Jack
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2580030/
https://www.ncbi.nlm.nih.gov/pubmed/19005572
http://dx.doi.org/10.1371/journal.pone.0003722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2580030/
https://www.ncbi.nlm.nih.gov/pubmed/19005572
http://dx.doi.org/10.1371/journal.pone.0003722

Ejemplares similares