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Indistinguishable Landscapes of Meiotic DNA Breaks in rad50(+) and rad50S Strains of Fission Yeast Revealed by a Novel rad50(+) Recombination Intermediate

The fission yeast Schizosaccharomyces pombe Rec12 protein, the homolog of Spo11 in other organisms, initiates meiotic recombination by creating DNA double-strand breaks (DSBs) and becoming covalently linked to the DNA ends of the break. This protein–DNA linkage has previously been detected only in m...

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Detalles Bibliográficos
Autores principales: Hyppa, Randy W., Cromie, Gareth A., Smith, Gerald R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2580034/
https://www.ncbi.nlm.nih.gov/pubmed/19023408
http://dx.doi.org/10.1371/journal.pgen.1000267