Product inhibition of secreted phospholipase A2 may explain lysophosphatidylcholines' unexpected therapeutic properties

BACKGROUND: Lysophosphatidylcholines (lysoPCs) are products of phospholipase A2 (PLA2) enzyme activity, and like the enzyme, have a direct role in toxic inflammatory responses in variety of organ systems. Paradoxically, reduced plasma lysoPC levels have been noted in sepsis patients and systemic tre...

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Detalles Bibliográficos
Autores principales: Cunningham, Timothy J, Yao, Lihua, Lucena, Angel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2580763/
https://www.ncbi.nlm.nih.gov/pubmed/18945345
http://dx.doi.org/10.1186/1476-9255-5-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2580763/
https://www.ncbi.nlm.nih.gov/pubmed/18945345
http://dx.doi.org/10.1186/1476-9255-5-17

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