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Product inhibition of secreted phospholipase A2 may explain lysophosphatidylcholines' unexpected therapeutic properties
BACKGROUND: Lysophosphatidylcholines (lysoPCs) are products of phospholipase A2 (PLA2) enzyme activity, and like the enzyme, have a direct role in toxic inflammatory responses in variety of organ systems. Paradoxically, reduced plasma lysoPC levels have been noted in sepsis patients and systemic tre...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2580763/ https://www.ncbi.nlm.nih.gov/pubmed/18945345 http://dx.doi.org/10.1186/1476-9255-5-17 |