Role of Amphipathic Helix of a Herpesviral Protein in Membrane Deformation and T Cell Receptor Downregulation

Lipid rafts are membrane microdomains that function as platforms for signal transduction and membrane trafficking. Tyrosine kinase interacting protein (Tip) of T lymphotropic Herpesvirus saimiri (HVS) is targeted to lipid rafts in T cells and downregulates TCR and CD4 surface expression. Here, we re...

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Detalles Bibliográficos
Autores principales: Min, Chan-Ki, Bang, Sun-Young, Cho, Bon-A, Choi, Yun-Hui, Yang, Jae-Seong, Lee, Sun-Hwa, Seong, Seung-Yong, Kim, Ki Woo, Kim, Sanguk, Jung, Jae Ung, Choi, Myung-Sik, Kim, Ik-Sang, Cho, Nam-Hyuk
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2581436/
https://www.ncbi.nlm.nih.gov/pubmed/19023411
http://dx.doi.org/10.1371/journal.ppat.1000209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2581436/
https://www.ncbi.nlm.nih.gov/pubmed/19023411
http://dx.doi.org/10.1371/journal.ppat.1000209

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