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Ca(2+) Signaling Occurs via Second Messenger Release from Intraorganelle Synthesis Sites
Cyclic ADP-ribose is an important Ca(2+)-mobilizing cytosolic messenger synthesized from β-NAD(+) by ADP-ribosyl cyclases (ARCs). However, the focus upon ectocellular mammalian ARCs (CD38 and CD157) has led to confusion as to how extracellular enzymes generate intracellular messengers in response to...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2581485/ https://www.ncbi.nlm.nih.gov/pubmed/18951023 http://dx.doi.org/10.1016/j.cub.2008.09.024 |