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The LPS-Induced Transcriptional Upregulation of the Chicken Lysozyme Locus Involves CTCF Eviction and Noncoding RNA Transcription
Transcription of the lysozyme gene is rapidly induced by proinflammatory stimuli such as treatment with bacterial lipopolysaccharide (LPS). Here we show that this induction involves both the relief of repression mediated by the enhancer-blocking protein CTCF that binds to a negative regulatory eleme...
Autores principales: | Lefevre, Pascal, Witham, James, Lacroix, Claire E., Cockerill, Peter N., Bonifer, Constanze |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2581490/ https://www.ncbi.nlm.nih.gov/pubmed/18851839 http://dx.doi.org/10.1016/j.molcel.2008.07.023 |
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