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The FANCM Ortholog Fml1 Promotes Recombination at Stalled Replication Forks and Limits Crossing Over during DNA Double-Strand Break Repair

The Fanconi anemia (FA) core complex promotes the tolerance/repair of DNA damage at stalled replication forks by catalyzing the monoubiquitination of FANCD2 and FANCI. Intriguingly, the core complex component FANCM also catalyzes branch migration of model Holliday junctions and replication forks in ...

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Detalles Bibliográficos
Autores principales: Sun, Weili, Nandi, Saikat, Osman, Fekret, Ahn, Jong Sook, Jakovleska, Jovana, Lorenz, Alexander, Whitby, Matthew C.
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2581491/
https://www.ncbi.nlm.nih.gov/pubmed/18851838
http://dx.doi.org/10.1016/j.molcel.2008.08.024