Cargando…
The FANCM Ortholog Fml1 Promotes Recombination at Stalled Replication Forks and Limits Crossing Over during DNA Double-Strand Break Repair
The Fanconi anemia (FA) core complex promotes the tolerance/repair of DNA damage at stalled replication forks by catalyzing the monoubiquitination of FANCD2 and FANCI. Intriguingly, the core complex component FANCM also catalyzes branch migration of model Holliday junctions and replication forks in ...
Autores principales: | Sun, Weili, Nandi, Saikat, Osman, Fekret, Ahn, Jong Sook, Jakovleska, Jovana, Lorenz, Alexander, Whitby, Matthew C. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2581491/ https://www.ncbi.nlm.nih.gov/pubmed/18851838 http://dx.doi.org/10.1016/j.molcel.2008.08.024 |
Ejemplares similares
-
The Fml1-MHF complex suppresses inter-fork strand annealing in fission yeast
por: Wong, Io Nam, et al.
Publicado: (2019) -
The RecQ DNA helicase Rqh1 constrains Exonuclease 1-dependent recombination at stalled replication forks
por: Osman, Fekret, et al.
Publicado: (2016) -
The ATPase activity of Fml1 is essential for its roles in homologous recombination and DNA repair
por: Nandi, Saikat, et al.
Publicado: (2012) -
How not to get cross(ed): A novel role for FANCM orthologs in meiotic recombination
por: Lorenz, Alexander, et al.
Publicado: (2012) -
Inter-Fork Strand Annealing causes genomic deletions during the termination of DNA replication
por: Morrow, Carl A, et al.
Publicado: (2017)