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Extracellular DNA Chelates Cations and Induces Antibiotic Resistance in Pseudomonas aeruginosa Biofilms

Biofilms are surface-adhered bacterial communities encased in an extracellular matrix composed of DNA, bacterial polysaccharides and proteins, which are up to 1000-fold more antibiotic resistant than planktonic cultures. To date, extracellular DNA has been shown to function as a structural support t...

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Detalles Bibliográficos
Autores principales: Mulcahy, Heidi, Charron-Mazenod, Laetitia, Lewenza, Shawn
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2581603/
https://www.ncbi.nlm.nih.gov/pubmed/19023416
http://dx.doi.org/10.1371/journal.ppat.1000213