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Specific Immunosuppression with Inducible Foxp3-Transduced Polyclonal T cells

Forkhead box p3 (Foxp3)-expressing regulatory T cells are key mediators of peripheral tolerance suppressing undesirable immune responses. Ectopic expression of Foxp3 confers regulatory T cell phenotype to conventional T cells, lending itself to therapeutic use in the prevention of autoimmunity and t...

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Detalles Bibliográficos
Autores principales: Andersen, Kristian G, Butcher, Tracey, Betz, Alexander G
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2581628/
https://www.ncbi.nlm.nih.gov/pubmed/18998771
http://dx.doi.org/10.1371/journal.pbio.0060276