Co-synthesis of Human δ-Aminolevulinate Dehydratase (ALAD) Mutants with the Wild-type Enzyme in Cell-free System—Critical Importance of Conformation on Enzyme Activity—

Properties of mutant δ-aminolevulinate dehydratase (ALAD) found in patients with ALAD porphyria were studied by enzymological and immunological analyses after the synthesis of enzyme complexes using a cell-free system. Enzyme activities of homozygous G133R, K59N/G133R, V153M, and E89K mutants were 1...

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Detalles Bibliográficos
Autores principales: Inoue, Rikako, Akagi, Reiko
Formato: Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2008
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2581755/
https://www.ncbi.nlm.nih.gov/pubmed/19015748
http://dx.doi.org/10.3164/jcbn.2008035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2581755/
https://www.ncbi.nlm.nih.gov/pubmed/19015748
http://dx.doi.org/10.3164/jcbn.2008035

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