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Co-synthesis of Human δ-Aminolevulinate Dehydratase (ALAD) Mutants with the Wild-type Enzyme in Cell-free System—Critical Importance of Conformation on Enzyme Activity—
Properties of mutant δ-aminolevulinate dehydratase (ALAD) found in patients with ALAD porphyria were studied by enzymological and immunological analyses after the synthesis of enzyme complexes using a cell-free system. Enzyme activities of homozygous G133R, K59N/G133R, V153M, and E89K mutants were 1...
Autores principales: | Inoue, Rikako, Akagi, Reiko |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
the Society for Free Radical Research Japan
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2581755/ https://www.ncbi.nlm.nih.gov/pubmed/19015748 http://dx.doi.org/10.3164/jcbn.2008035 |
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