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The Trouble with Sliding Windows and the Selective Pressure in BRCA1
Sliding-window analysis has widely been used to uncover synonymous (silent, d(S)) and nonsynonymous (replacement, d(N)) rate variation along the protein sequence and to detect regions of a protein under selective constraint (indicated by d(N)<d(S)) or positive selection (indicated by d(N)>d(S)...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
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Public Library of Science
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2581807/ https://www.ncbi.nlm.nih.gov/pubmed/19015730 http://dx.doi.org/10.1371/journal.pone.0003746 |