Wiskott-Aldrich syndrome protein deficiency in B cells results in impaired peripheral homeostasis

To more precisely identify the B-cell phenotype in Wiskott-Aldrich syndrome (WAS), we used 3 distinct murine in vivo models to define the cell intrinsic requirements for WAS protein (WASp) in central versus peripheral B-cell development. Whereas WASp is dispensable for early bone marrow B-cell devel...

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Detalles Bibliográficos
Autores principales: Meyer-Bahlburg, Almut, Becker-Herman, Shirly, Humblet-Baron, Stephanie, Khim, Socheath, Weber, Michele, Bouma, Gerben, Thrasher, Adrian J., Batista, Facundo D., Rawlings, David J.
Formato: Texto
Lenguaje:English
Publicado: American Society of Hematology 2008
Materias:
Immunobiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582000/
https://www.ncbi.nlm.nih.gov/pubmed/18687984
http://dx.doi.org/10.1182/blood-2008-02-140814

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582000/
https://www.ncbi.nlm.nih.gov/pubmed/18687984
http://dx.doi.org/10.1182/blood-2008-02-140814

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