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Adaptation to cell culture induces functional differences in measles virus proteins
BACKGROUND: Live, attenuated measles virus (MeV) vaccine strains were generated by adaptation to cell culture. The genetic basis for the attenuation of the vaccine strains is unknown. We previously reported that adaptation of a pathogenic, wild-type MeV to Vero cells or primary chicken embryo fibrob...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582235/ https://www.ncbi.nlm.nih.gov/pubmed/18954437 http://dx.doi.org/10.1186/1743-422X-5-129 |