Ser649 and Ser650 Are the Major Determinants of Protein Kinase A-Mediated Activation of Human Hormone-Sensitive Lipase against Lipid Substrates

BACKGROUND: Hormone-sensitive lipase (HSL) is a key enzyme in the mobilization of fatty acids from stored triacylglycerols. Its activity is regulated by reversible protein phosphorylation. In rat HSL Ser563, Ser659 and Ser660 have been shown to be phosphorylated by protein kinase A (PKA) in vitro as...

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Detalles Bibliográficos
Autores principales: Krintel, Christian, Osmark, Peter, Larsen, Martin R., Resjö, Svante, Logan, Derek T., Holm, Cecilia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582450/
https://www.ncbi.nlm.nih.gov/pubmed/19018281
http://dx.doi.org/10.1371/journal.pone.0003756

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582450/
https://www.ncbi.nlm.nih.gov/pubmed/19018281
http://dx.doi.org/10.1371/journal.pone.0003756

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