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The Marine-Derived Oligosaccharide Sulfate (MdOS), a Novel Multiple Tyrosine Kinase Inhibitor, Combats Tumor Angiogenesis both In Vitro and In Vivo

Despite the emerging success of multi-targeted protein tyrosine kinase (PTK) inhibitors in cancer therapy, significant side effects and resistance concerns seems to be avoided unlikely. The aim of the present study was to identify novel multi-targeting PTK inhibitors. The kinase enzymatic activities...

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Detalles Bibliográficos
Autores principales: Ma, Jingui, Xin, Xianliang, Meng, Linghua, Tong, Linjiang, Lin, Liping, Geng, Meiyu, Ding, Jian
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582481/
https://www.ncbi.nlm.nih.gov/pubmed/19020661
http://dx.doi.org/10.1371/journal.pone.0003774