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Unifying evolutionary and thermodynamic information for RNA folding of multiple alignments

Computational methods for determining the secondary structure of RNA sequences from given alignments are currently either based on thermodynamic folding, compensatory base pair substitutions or both. However, there is currently no approach that combines both sources of information in a single optimi...

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Detalles Bibliográficos
Autores principales: Seemann, Stefan E., Gorodkin, Jan, Backofen, Rolf
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582601/
https://www.ncbi.nlm.nih.gov/pubmed/18836192
http://dx.doi.org/10.1093/nar/gkn544