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Unifying evolutionary and thermodynamic information for RNA folding of multiple alignments
Computational methods for determining the secondary structure of RNA sequences from given alignments are currently either based on thermodynamic folding, compensatory base pair substitutions or both. However, there is currently no approach that combines both sources of information in a single optimi...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582601/ https://www.ncbi.nlm.nih.gov/pubmed/18836192 http://dx.doi.org/10.1093/nar/gkn544 |