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The Cohesin loading factor NIPBL recruits histone deacetylases to mediate local chromatin modifications
Cornelia de Lange Syndrome (CdLS) is a rare congenital malformation disorder. About half of the patients with CdLS carry mutations in the NIPBL gene encoding the NIPBL protein, a subunit of the Cohesin loading complex. Recent studies show association of Cohesin with chromatin-remodeling complexes, e...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582609/ https://www.ncbi.nlm.nih.gov/pubmed/18854353 http://dx.doi.org/10.1093/nar/gkn688 |