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Delivery of steric block morpholino oligomers by (R-X-R)(4) peptides: structure–activity studies
Redirecting the splicing machinery through the hybridization of high affinity, RNase H- incompetent oligonucleotide analogs such as phosphoramidate morpholino oligonucleotides (PMO) might lead to important clinical applications. Chemical conjugation of PMO to arginine-rich cell penetrating peptides...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582615/ https://www.ncbi.nlm.nih.gov/pubmed/18796528 http://dx.doi.org/10.1093/nar/gkn541 |