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Novel mechanism of hexamer ring assembly in protein/RNA interactions revealed by single molecule imaging

Many nucleic acid-binding proteins and the AAA+ family form hexameric rings, but the mechanism of hexamer assembly is unclear. It is generally believed that the specificity in protein/RNA interaction relies on molecular contact through a surface charge or 3D structure matching via conformational cap...

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Detalles Bibliográficos
Autores principales: Xiao, Feng, Zhang, Hui, Guo, Peixuan
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582624/
https://www.ncbi.nlm.nih.gov/pubmed/18940870
http://dx.doi.org/10.1093/nar/gkn669