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Rad51 gain-of-function mutants that exhibit high affinity DNA binding cause DNA damage sensitivity in the absence of Srs2
We previously identified several rad51 gain-of-function alleles that partially suppress the requirement for RAD55 and RAD57 in DNA repair. To gain further insight into the mechanism of action of these alleles, we compared the activities of Rad51-V328A, Rad51-P339S and Rad51-I345T with wild-type Rad5...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
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Oxford University Press
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582631/ https://www.ncbi.nlm.nih.gov/pubmed/18927106 http://dx.doi.org/10.1093/nar/gkn720 |