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Targeting the UPS as therapy in multiple myeloma
The coordinated regulation of cellular protein synthesis and degradation is essential for normal cellular functioning. The ubiquitin proteasome system mediates the intracellular protein degradation that is required for normal cellular homeostasis. The 26S proteasome is a multi-enzyme protease that d...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582802/ https://www.ncbi.nlm.nih.gov/pubmed/19007431 http://dx.doi.org/10.1186/1471-2091-9-S1-S1 |